Researchers at UK’s University of Cambridge believe they can create a class of Covid-19 killer drugs using a gene-cutting technology that could use artificial enzymes to surgically cut the virus’ RNA genome.
From Scientific American:
Popular CRISPR gene-editing tools can also target RNA, but the human immune system sometimes reacts poorly to the bacterial enzymes used. XNAzymes are not found in nature, making them less likely to trigger an immune system attack. They also don’t rely on co-opting extra components from within the cell; this might reduce side effects. “All contemporary RNA treatments make use of cellular machinery,” says biomedical engineer Roy van der Meel of Eindhoven University of Technology in the Netherlands, who was not involved in the new research. “This is a pair of stand-alone scissors.”
The breakthrough promises to threaten the use of Covid-19 as another round of lockdowns and vaccine mandates, so critics are skeptical of any effective follow-up to these initial findings.
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